The talk show maven told Good Housekeeping she doesn't believe she would have been a "good mum for babies" and she "didn't want babies".
Winfrey says this in the April U.K. edition of the magazine.
She says didn’t have the “patience” for kids.
The 63-year old new "60 Minutes" contributor also says she knew she would not regret her decision.
She also talks about her weightloss in the magazine.
The issue hits newsstands March 1.